Single Use Systems
Hybrid Systems
Balancing flexibility and consistent performance
Modern biopharmaceutical facilities increasingly rely on hybrid process architectures that combine stainless-steel equipment with single-use components. This approach enables flexible production while maintaining consistent process performance. ZETA designs integrated systems that incorporate:
- Stainless-steel vessels and reactors with disposable flow paths
- Single-use mixing and transfer assemblies
- Integration with upstream and downstream processing systems, including filtration and buffer operations
These systems are engineered as coordinated process environments that support both clinical and commercial manufacturing.
Engineering and automation for hybrid systems
Hybrid systems require coordinated engineering and automation to maintain reliable operation across disposable and fixed equipment.
- Integrated automation and control systems
- Monitoring of critical process parameters
- Recipe-driven process operation
- Connection to plant-wide control architectures
Flexible manufacturing applications
Hybrid single-use systems support manufacturing environments requiring flexibility and rapid product changeover.
- Clinical and pilot manufacturing
- Multiproduct biologics facilities
- Cell & gene therapy production
- Process development and scale-up
Modular hybrid systems for scalable deployment
Single-use technologies are often implemented within modular skid systems designed for scalable deployment.
- Integrated process platforms
- Hygienic fluid path design
- Automated disposable components
- Efficient installation and commissioning
Related Resources Single Use Systems
Interview: Maximilian van de Graaf on the integration of Single-Use Systems
